Entries by Amar Safdar

Listeriosis in recipients of allogeneic blood and marrow transplantation: thirteen year review of disease characteristics, treatment outcomes and a new association with human cytomegalovirus infection.

Safdar A, Papadopoulous EB, Armstrong D. Bone Marrow Transplant. 2002 Jun;29(11):913-6. Abstract Listeriosis is uncommon in recipients of allogeneic blood, marrow and organ transplantation. Six patients with systemic Listeria monocytogenes infection during 1985-1997 at Bone Marrow Transplantation Service, Memorial Sloan-Kettering Cancer Center are described. In two male and four female patients, the median duration from […]

Intracranial perineural extension of invasive mycosis: a novel mechanism of disease propagation by Aspergillus fumigatus.

Safdar A, Dommers MP Jr, Talwani R, Thompson CR. Clin Infect Dis. 2002 Sep 1;35(5):e50-3. Epub 2002 Aug 1. Abstract We describe an immunocompetent woman who had refractory, invasive sphenoid sinus Aspergillus fumigatus infection for which there was radiologic evidence of intracranial perineural spread. The patient responded to a combination of antifungal and adjuvant recombinant […]

Prospective, multicenter surveillance study of Candida glabrata: fluconazole and itraconazole susceptibility profiles in bloodstream, invasive, and colonizing strains and differences between isolates from three urban teaching hospitals in New York City (Candida Susceptibility Trends Study, 1998 to 1999).

Safdar A, Chaturvedi V, Koll BS, Larone DH, Perlin DS, Armstrong D. Antimicrob Agents Chemother. 2002 Oct;46(10):3268-72. Abstract Since the 1990s, the substantial increase in the rate of Candida glabrata infections has become a serious problem. As most C. glabrata infections arise from the host’s endogenous microflora, the present prospective, multicenter analysis included all clinical […]

Hematogenous infections due to Candida parapsilosis: changing trends in fungemic patients at a comprehensive cancer center during the last four decades.

Safdar A, Perlin DS, Armstrong D. Diagn Microbiol Infect Dis. 2002 Sep;44(1):11-6. Abstract This study was performed to evaluate trends in species distribution in patients’ with hematogenous candidiasis at a comprehensive cancer center. The results of a retrospective analysis from January 1, 1993 to December 31, 1998 were compared with prior reports from Memorial Sloan-Kettering […]

Fatal immune restoration disease in human immunodeficiency virus type 1-infected patients with progressive multifocal leukoencephalopathy: impact of antiretroviral therapy-associated immune reconstitution.

Safdar A, Rubocki RJ, Horvath JA, Narayan KK, Waldron RL. Clin Infect Dis. 2002 Nov 15;35(10):1250-7. Epub 2002 Oct 28. Abstract Immune reconstitution resulting from use of highly active antiretroviral therapy in patients infected with human immunodeficiency virus type 1 (HIV-1) has been associated with a significant decrease in infectious morbidity and with improved survival. […]

Prospective evaluation of Candida species colonization in hospitalized cancer patients: impact on short-term survival in recipients of marrow transplantation and patients with hematological malignancies.

Safdar A, Armstrong D. Bone Marrow Transplant. 2002 Dec;30(12):931-5. Abstract Most hematogenous candidiasis originates from endogenous host flora. The impact of clinically prominent Candida colonization on short-term mortality (<or=14 weeks) was prospectively studied in 193 hospitalized patients from 1998 to 1999. Clinically prominent colonization included yeasts isolated from all sterile body sites and >50 colonies […]