Entries by Amar Safdar

Prospective study of Candida species in patients at a comprehensive cancer center.

Safdar A, Chaturvedi V, Cross EW, Park S, Bernard EM, Armstrong D, Perlin DS. Antimicrob Agents Chemother. 2001 Jul;45(7):2129-33. Abstract Since most nosocomial systemic yeast infections arise from the endogenous flora of the patient, we prospectively evaluated the species stratification and antifungal susceptibility profile of Candida spp. associated with heavy colonization and systemic infection in […]

Infectious morbidity in critically ill patients with cancer.

Safdar A, Armstrong D. Crit Care Clin. 2001 Jul;17(3):531-70, vii-viii. Review. Abstract Infection frequently complicates the course of cancer treatment and often adversely affects the outcome. Patients have a greater tendency for acquiring infections caused by opportunistic microorganisms. Agents with low virulence potential may lead to invasive and often life-threatening infections because of altered host […]

Candida glabrata and Candida krusei fungemia after high-risk allogeneic marrow transplantation: no adverse effect of low-dose fluconazole prophylaxis on incidence and outcome.

Safdar A, van Rhee F, Henslee-Downey JP, Singhal S, Mehta J. Bone Marrow Transplant. 2001 Nov;28(9):873-8. Abstract Candidemia is a serious complication in patients following allogeneic blood, marrow, and organ transplantation. Fourteen patients developed nosocomial fungemia among 204 allogeneic marrow transplants performed during 1997-1999. Incidence of hematogenous candidiasis was 6.8 per 100 allogeneic BMT. All […]

Progressive cutaneous hyalohyphomycosis due to Paecilomyces lilacinus: rapid response to treatment with caspofungin and itraconazole.

Safdar A. Clin Infect Dis. 2002 May 15;34(10):1415-7. Epub 2002 Apr 23. Abstract A case of rapidly progressive cutaneous infection due to Paecilomyces lilacinus developed in a woman with advanced pancreatic cancer who did not have granulocytopenia. The infection responded favorably to caspofungin and itraconazole combination therapy.

Prosthetic valve endocarditis due to vancomycin-resistant Enterococcus faecium: treatment with chloramphenicol plus minocycline.

Safdar A, Bryan CS, Stinson S, Saunders DE. Clin Infect Dis. 2002 Jun 1;34(11):E61-3. Epub 2002 May 9. Abstract We report a case of prosthetic valve endocarditis and persistent bacteremia due to vancomycin-resistant Enterococcus faecium. The combination of parenteral chloramphenicol plus minocycline therapy was administered for 8 weeks and resulted in cure after treatment with […]