Entries by Amar Safdar

Mycobacterium tuberculosis at a comprehensive cancer centre: active disease in patients with underlying malignancy during 1990-2000.

De La Rosa GR, Jacobson KL, Rolston KV, Raad II, Kontoyiannis DP, Safdar A. Clin Microbiol Infect. 2004 Aug;10(8):749-52. Abstract Thirty HIV-seronegative cancer patients with active tuberculosis were evaluated. Eighteen (60%) were immigrants, 19 (63%) had haematological malignancy, and fever was the most common presentation (97%). Of 19 (63%) patients with pulmonary tuberculosis, 11 (58%) were […]

Antimicrobial susceptibility of 128 Salmonella enterica serovar typhi and paratyphi A isolates from northern India.

Safdar A, Kaur H, Elting L, Rolston KV. Chemotherapy. 2004 Jun;50(2):88-91. Abstract Most systemic Salmonella enterica serovar typhi and paratyphi A infections diagnosed in the United States (up to 70%) are acquired during travel to regions of high endemicity. Increasing resistance to agents commonly used for the treatment of such infections (including multidrug resistant isolates) […]

Clinical significance of non-Candida fungal blood isolation in patients undergoing high-risk allogeneic hematopoietic stem cell transplantation (1993-2001).

Safdar A, Singhal S, Mehta J. Cancer. 2004 Jun 1;100(11):2456-61. Abstract BACKGROUND: The clinical relevance of mold isolated from blood cultures, even in severely immunosuppressed allogeneic hematopoietic stem cell transplantation (HSCT) recipients, remains uncertain. The authors hypothesized that isolation of non-Candida fungi from blood cultures in patients undergoing high-risk HSCT would have clinical significance. METHODS: […]

The predictors of outcome in immunocompetent patients with hematogenous candidiasis.

Safdar A, Bannister TW, Safdar Z. Int J Infect Dis. 2004 May;8(3):180-6. Abstract OBJECTIVE: Clinical parameters that predict outcome in non-immunosuppressed candidemic patients are not fully understood. METHODS: Eighty-one consecutive episodes of candidemia were retrospectively evaluated in 75 patients during 1998-2000. RESULTS: Infection due to Candida albicans was common (n = 30; 37%) followed by […]

Strongyloidiasis in patients at a comprehensive cancer center in the United States.

Safdar A, Malathum K, Rodriguez SJ, Husni R, Rolston KV. Cancer. 2004 Apr 1;100(7):1531-6. Abstract BACKGROUND: The frequency of Strongyloides stercoralis infestation and complication in patients with cancer in the United States is unknown. METHODS: The authors performed a retrospective analysis of S. stercoralis infection in patients who were undergoing cancer treatment at The University […]

Curvularia–favorable response to oral itraconazole therapy in two patients with locally invasive phaeohyphomycosis.

Safdar A. Clin Microbiol Infect. 2003 Dec;9(12):1219-23. Abstract Curvularia species are ubiquitous and occasionally lead to infections in humans. In immunosuppressed patients, infections are often serious, and systemic dissemination is not uncommon. The optimal antifungal therapy is unclear. I here present two cases, a healthy man with locally invasive, mulicentric paranasal fungal sinusitis, and a […]